Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease

Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease

<p>Abstract</p> <p>Background</p> <p>Juvenile Idiopathic Arthritis (JIA) is a complex autoimmune rheumatic disease of largely unknown cause. Evidence is growing that epigenetic variation, particularly DNA methylation, is associated with autoimmune disease. However, noth...

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Bibliographic Details
Main Authors: Ellis Justine A, Munro Jane E, Chavez Raul A, Gordon Lavinia, Joo Jihoon E, Akikusa Jonathan D, Allen Roger C, Ponsonby Anne-Louise, Craig Jeffrey M, Saffery Richard
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Clinical Epigenetics
Subjects:
Epigenetics
Juvenile idiopathic arthritis
DNA methylation
Autoimmunity
Methylome
Methotrexate
Online Access:http://www.clinicalepigeneticsjournal.com/content/4/1/20

Internet

http://www.clinicalepigeneticsjournal.com/content/4/1/20

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