Refinement of AlphaFold2 models against experimental and hybrid cryo-EM density maps

Recent breakthroughs in deep learning-based protein structure prediction show that it is possible to obtain highly accurate models for a wide range of difficult protein targets for which only the amino acid sequence is known. The availability of accurately predicted models from sequences can potenti...

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Bibliographic Details
Main Authors: Maytha Alshammari, Willy Wriggers, Jiangwen Sun, Jing He
Format: Article
Language:English
Published: Cambridge University Press 2022-01-01
Series:QRB Discovery
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2633289222000138/type/journal_article