PMINR: Pointwise Mutual Information-Based Network Regression – With Application to Studies of Lung Cancer and Alzheimer’s Disease

Complex diseases are believed to be the consequence of intracellular network(s) involving a range of factors. An improved understanding of a disease-predisposing biological network could lead to better identification of genes and pathways that confer disease risk and therefore inform drug developmen...

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Bibliographic Details
Main Authors: Weiqiang Lin, Jiadong Ji, Yuchen Zhu, Mingzhuo Li, Jinghua Zhao, Fuzhong Xue, Zhongshang Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.556259/full