Thromboelastography and thrombin generation assessments for pediatric severe hemophilia A patients are highly variable and not predictive of clinical phenotypes

Thromboelastography and thrombin generation assessments for pediatric severe hemophilia A patients are highly variable and not predictive of clinical phenotypes

Abstract Background Severe hemophilia A (SHA) patients vary in severity of bleeding, arthropathy, and requirements for replacement factor VIII (FVIII). Baseline hemostatic activity assays using calibrated automated thrombography (CAT) and thromboelastography (TEG) may offer insights into the physiol...

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Bibliographic Details
Main Authors: Natalie Mathews, Fred G. Pluthero, Margaret L. Rand, Ann Marie Stain, Manuel Carcao, Victor S. Blanchette, Walter H. A. Kahr
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
hemophilia
hemostasis
platelets
thrombin generation
thromboelastography
Online Access:https://doi.org/10.1002/rth2.12800

Internet

https://doi.org/10.1002/rth2.12800

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