The association of genomic alterations with PD‐L1 expression in Chinese patients with EGFR/ALK wild‐type lung adenocarcinoma and potential predictive value of Hippo pathway mutations to immunotherapy

The association of genomic alterations with PD‐L1 expression in Chinese patients with EGFR/ALK wild‐type lung adenocarcinoma and potential predictive value of Hippo pathway mutations to immunotherapy

Abstract Background The study focuses on PD‐L1 expression as an essential biomarker for gauging the response of EGFR/ALK wild‐type NSCLC patients to FDA‐approved immune checkpoint inhibitors (ICIs). It aims to explore clinical, molecular, and immune microenvironment characteristics associated with P...

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Bibliographic Details
Main Authors: Fangfang Liu, Xuemei Zhang, Mengyao Lu, Chun Liu, Xiaodong Zhang, Qian Chu, Yuan Chen, Peng Zhang
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Cancer Medicine
Subjects:
adenocarcinoma
Hippo
immunotherapy
NSCLC
PD‐L1
tumor immune microenvironment
Online Access:https://doi.org/10.1002/cam4.7038

Internet

https://doi.org/10.1002/cam4.7038

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