Isotretinoin Exposure and Risk of Celiac Disease.

Isotretinoin (13-cis retinoic acid) is a metabolite of vitamin A and has anti-inflammatory and immunoregulatory effects; however, a recent publication by DePaolo et al. demonstrated that in the presence of IL-15, retinoic acid can act as an adjuvant and promote inflammation against dietary proteins....

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Bibliographic Details
Main Authors: Shadi Rashtak, Shahryar Khaleghi, Eric V Marietta, Mark R Pittelkow, Joseph J Larson, Brian D Lahr, Joseph A Murray
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4544877?pdf=render