In Vitro and In Silico Potential Inhibitory Effects of New Biflavonoids from <i>Ochna rhizomatosa</i> on HIV-1 Integrase and <i>Plasmodium falciparum</i>

In Vitro and In Silico Potential Inhibitory Effects of New Biflavonoids from <i>Ochna rhizomatosa</i> on HIV-1 Integrase and <i>Plasmodium falciparum</i>

The aim of this study was to identify bioactive secondary metabolites from <i>Ochna rhizomatosa</i> with potential inhibitory effects against HIV and <i>Plasmodium falciparum. A</i> phytochemical study of <i>O. rhizomatosa</i> root barks resulted in the identifica...

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Bibliographic Details
Main Authors: Angélique Nicolas Messi, Susan Lucia Bonnet, Brice Ayissi Owona, Anke Wilhelm, Eutrophe Le Doux Kamto, Joseph Thierry Ndongo, Xavier Siwe-Noundou, Madan Poka, Patrick H. Demana, Rui W. M. Krause, Joséphine Ngo Mbing, Dieudonné Emmanuel Pegnyemb, Christian G. Bochet
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
<i>Ochna rhizomatosa</i>
biflavonoids
HIV-1 replication
<i>Plasmodium falciparum</i> NF<i>54</i>
structure–activity relationships
molecular docking
Online Access:https://www.mdpi.com/1999-4923/14/8/1701

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https://www.mdpi.com/1999-4923/14/8/1701

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