Exploring lncRNAs associated with human pancreatic islet cell death induced by transfer of adoptive lymphocytes in a humanized mouse model

Exploring lncRNAs associated with human pancreatic islet cell death induced by transfer of adoptive lymphocytes in a humanized mouse model

BackgroundLong noncoding RNA (lncRNA)-mediated posttranscriptional and epigenetic landscapes of gene regulation are associated with numerous human diseases. However, the regulatory mechanisms governing human β-cell function and survival remain unknown. Owing to technical and ethical constraints, stu...

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Bibliographic Details
Main Authors: Md Munir Hossain, Regan Roat, Jenica Christopherson, Colette Free, Ansarullah, Brian James, Zhiguang Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Endocrinology
Subjects:
lncRNA
ß-cell
pancreatic islet
T1D
T2D
humanized mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1244688/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1244688/full

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