The Pre-Transplant Non-HLA Antibody Burden Associates With the Development of Histology of Antibody-Mediated Rejection After Kidney Transplantation

The Pre-Transplant Non-HLA Antibody Burden Associates With the Development of Histology of Antibody-Mediated Rejection After Kidney Transplantation

BackgroundMany kidney allografts fail due to the occurrence of antibody-mediated rejection (ABMR), related to donor-specific anti-HLA antibodies (HLA-DSA). However, the histology of ABMR can also be observed in patients without HLA-DSA. While some non-HLA antibodies have been related to the histolog...

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Bibliographic Details
Main Authors: Aleksandar Senev, Bryan Ray, Evelyne Lerut, Jayasree Hariharan, Christine Heylen, Dirk Kuypers, Ben Sprangers, Marie-Paule Emonds, Maarten Naesens
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
non-HLA antibodies
autoimmunity
kidney transplantation
graft outcome
rejection
graft failure
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.809059/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.809059/full

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