Solid-Phase Synthesis of Arylpiperazine Derivatives and Implementation of the Distributed Drug Discovery (D3) Project in the Search for CNS Agents

Solid-Phase Synthesis of Arylpiperazine Derivatives and Implementation of the Distributed Drug Discovery (D3) Project in the Search for CNS Agents

We have successfully implemented the concept of Distributed Drug Discovery (D3) in the search for CNS agents. Herein, we demonstrate, for the first time, student engagement from different sites around the globe in the development of new biologically active compounds. As an outcome we have synthesize...

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Bibliographic Details
Main Authors: William L. Scott, Ziniu Zhou, Martin J. O’Donnell, Grzegorz Satała, Andrzej J. Bojarski, Jean Martinez, Gaël Nomezine, Maciej Pawłowski, Gilles Subra, Katarzyna Grychowska, Joanna Król, Paweł Zajdel
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:Molecules
Subjects:
Distributed Drug Discovery (D3)
combinatorial chemistry
solid-phase synthesis
SynPhase Lanterns
long-chain arylpiperazines
succinimides
5-HT1A
5-HT2A receptor affinity
Online Access:http://www.mdpi.com/1420-3049/16/5/4104/

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http://www.mdpi.com/1420-3049/16/5/4104/

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