A novel protein isoform of the multicopy human NAIP gene derives from intragenic Alu SINE promoters.

The human neuronal apoptosis inhibitory protein (NAIP) gene is no longer principally considered a member of the Inhibitor of Apoptosis Protein (IAP) family, as its domain structure and functions in innate immunity also warrant inclusion in the Nod-Like Receptor (NLR) superfamily. NAIP is located in...

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Bibliographic Details
Main Authors: Mark T Romanish, Hisae Nakamura, C Benjamin Lai, Yuzhuo Wang, Dixie L Mager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2685007?pdf=render