Deformation-based morphometry identifies deep brain structures protected by ocrelizumab

Background: Despite advancements in treatments for multiple sclerosis, insidious disease progression remains an area of unmet medical need, for which atrophy-based biomarkers may help better characterize the progressive biology. Methods: We developed and applied a method of longitudinal deformation-...

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Bibliographic Details
Main Authors: Zhuang Song, Anithapriya Krishnan, Laura Gaetano, Nicholas J. Tustison, David Clayton, Alex de Crespigny, Thomas Bengtsson, Xiaoming Jia, Richard A.D. Carano
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158222000249