Genetic diversity in the transmission-blocking vaccine candidate Plasmodium vivax gametocyte protein Pvs230 from the China–Myanmar border area and central Myanmar

Genetic diversity in the transmission-blocking vaccine candidate Plasmodium vivax gametocyte protein Pvs230 from the China–Myanmar border area and central Myanmar

Abstract Background Sexual stage surface antigens are potential targets of transmission-blocking vaccines (TBVs). The gametocyte and gamete surface antigen P230, a leading TBV candidate, is critical for red blood cell binding during exflagellation and subsequent oocyst development. Here, the genetic...

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Bibliographic Details
Main Authors: Xin Zhao, Yubing Hu, Yan Zhao, Lin Wang, Zifang Wu, Myat Thu Soe, Myat Phone Kyaw, Liwang Cui, Xiaotong Zhu, Yaming Cao
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Parasites & Vectors
Subjects:
Plasmodium vivax
Pvs230
Gamete
Transmission-blocking vaccine
Genetic diversity
Online Access:https://doi.org/10.1186/s13071-022-05523-0

Internet

https://doi.org/10.1186/s13071-022-05523-0

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