Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling
The progenitor cells of the developing liver can differentiate toward both hepatocyte and biliary cell fates. In addition to the established roles of TGFβ and Notch signaling in this fate specification process, there is increasing evidence that liver progenitors are sensitive to mechanical cues. Her...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-12-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/38536 |