Bioelectrochemistry of nucleic acids for early cancer diagnostics – analysis of DNA methylation and detection of microRNAs
Dysregulation of gene expression mechanisms has been observed in many tumors, making their analysis of utmost importance. These mechanisms include DNA methylation, an epigenetic mechanism in which 5-carbon of cytosine becomes methylated, leading to gene silencing, and action of short RNA molecules c...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2017-03-01
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| Series: | Reviews in Analytical Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/revac-2016-0022 |