Increased Expression of MicroRNA‐206 Inhibits Potassium Voltage‐Gated Channel Subfamily A Member 5 in Pulmonary Arterial Smooth Muscle Cells and Is Related to Exaggerated Pulmonary Artery Hypertension Following Intrauterine Growth Retardation in Rats

Increased Expression of MicroRNA‐206 Inhibits Potassium Voltage‐Gated Channel Subfamily A Member 5 in Pulmonary Arterial Smooth Muscle Cells and Is Related to Exaggerated Pulmonary Artery Hypertension Following Intrauterine Growth Retardation in Rats

Background Intrauterine growth retardation (IUGR) is related to pulmonary artery hypertension in adults, and microRNA‐206 (miR‐206) is proposed to affect the proliferation and apoptosis of pulmonary artery smooth muscle cells (PASMCs) via post‐transcriptional regulation. Methods and Results In an IU...

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Bibliographic Details
Main Authors: Ying Lv, Linchen Fu, Ziming Zhang, Weizhong Gu, Xiaofei Luo, Ying Zhong, Shanshan Xu, Yu Wang, Lingling Yan, Min Li, Lizhong Du
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
epigenetics
K‐channel
Kv1.5
microRNA
microRNA‐206
PAH
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.010456

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.118.010456

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