Single-cell Transcriptomic Analysis Reveals the Cellular Heterogeneity of Mesenchymal Stem Cells

Single-cell Transcriptomic Analysis Reveals the Cellular Heterogeneity of Mesenchymal Stem Cells

Ex vivo-expanded mesenchymal stem cells (MSCs) have been demonstrated to be a heterogeneous mixture of cells exhibiting varying proliferative, multipotential, and immunomodulatory capacities. However, the exact characteristics of MSCs remain largely unknown. By single-cell RNA sequencing of 61,296 M...

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Bibliographic Details
Main Authors: Chen Zhang, Xueshuai Han, Jingkun Liu, Lei Chen, Ying Lei, Kunying Chen, Jia Si, Tian-yi Wang, Hui Zhou, Xiaoyun Zhao, Xiaohui Zhang, Yihua An, Yueying Li, Qian-Fei Wang
Format: Article
Language:English
Published: Oxford University Press 2022-02-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Mesenchymal stem cell
Single-cell RNA sequencing
Heterogeneity
Lineage trajectory
Immune regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022922000122

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http://www.sciencedirect.com/science/article/pii/S1672022922000122

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