Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid–Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario

Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid–Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario

Autoimmune polyendocrine syndrome (APS) is assumed to involve an immune system malfunction and entails several autoimmune diseases co-occurring in different tissues of the same patient; however, they are orphans of its accurate diagnosis, as its genetic basis and pathogenic mechanism are not underst...

Full description

Bibliographic Details
Main Authors: Oriol Calvete, José Reyes, Hernán Valdés-Socin, Paloma Martin, Mónica Marazuela, Alicia Barroso, Javier Escalada, Antoni Castells, Raúl Torres-Ruiz, Sandra Rodríguez-Perales, María Currás-Freixes, Javier Benítez
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
gastric neuroendocrine tumors (gNETS)
autoimmune thyrogastric syndrome
autoimmune polyendocrine syndrome (APS)
achlorhydria
solute carriers (SLCs)
immunodeficiencies
Online Access:https://www.mdpi.com/2073-4409/10/12/3500

Internet

https://www.mdpi.com/2073-4409/10/12/3500

Similar Items