Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis

Abstract Biomarkers are needed for predicting the effectiveness of disease modifying antirheumatic drugs (DMARDs). Here, using functional lipid mediator profiling and deeply phenotyped patients with early rheumatoid arthritis (RA), we observe that peripheral blood  specialized pro-resolving mediator...

Полное описание

Библиографические подробности
Главные авторы: Esteban A. Gomez, Romain A. Colas, Patricia R. Souza, Rebecca Hands, Myles J. Lewis, Conrad Bessant, Costantino Pitzalis, Jesmond Dalli
Формат: Статья
Язык:English
Опубликовано: Nature Portfolio 2020-10-01
Серии:Nature Communications
Online-ссылка:https://doi.org/10.1038/s41467-020-19176-z