Molecular basis for polysaccharide recognition and modulated ATP hydrolysis by the O antigen ABC transporter

Gram negative microbes strategically equip lipopolysaccharides with O antigens to expand the extracellular envelope. Here, the authors examine how the O antigen is captured by a special class of ABC transporters containing a carbohydrate-binding module accessory.

Bibliographic Details
Main Authors: Nicholas Spellmon, Artur Muszyński, Ireneusz Górniak, Jiri Vlach, David Hahn, Parastoo Azadi, Jochen Zimmer
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32597-2