Molecular signatures distinguish senescent cells from inflammatory cells in aged mouse callus stromal cells

Molecular signatures distinguish senescent cells from inflammatory cells in aged mouse callus stromal cells

Cellular senescence plays important roles in age-related diseases, including musculoskeletal disorders. Senescent cells (SCs) exert a senescence-associated secretory phenotype (SASP) by producing SASP factors, some of which overlap with factors produced by inflammatory cells (Inf-Cs). However, the d...

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Bibliographic Details
Main Authors: Jiatong Liu, Xi Lin, Andrew McDavid, Yutiancheng Yang, Hengwei Zhang, Brendan F. Boyce, Lianping Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Endocrinology
Subjects:
inflammation
ScRNA-seq
aging
fracture
senescence
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1090049/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1090049/full

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