The role of E-cadherin in neoplastic evolution of epithelial cells

Interaction of the extracellular domains of the transmembrane proteins cadherins provides cell-cell adhesion. For many years epithelial E- cadherin was regarded as a tumor suppressor and was used as a prognostic marker in cancer. Suppression of E-cadherin expression was observed in many carcinomas....

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Bibliographic Details
Main Authors: N. A. Gloushankova, I. Yu. Zhitnyak, D. V. Ayollo, S. N. Rubtsova
Format: Article
Language:Russian
Published: ABV-press 2015-06-01
Series:Успехи молекулярной онкологии
Subjects:
Online Access:https://umo.abvpress.ru/jour/article/view/12