The role of E-cadherin in neoplastic evolution of epithelial cells
Interaction of the extracellular domains of the transmembrane proteins cadherins provides cell-cell adhesion. For many years epithelial E- cadherin was regarded as a tumor suppressor and was used as a prognostic marker in cancer. Suppression of E-cadherin expression was observed in many carcinomas....
Main Authors: | N. A. Gloushankova, I. Yu. Zhitnyak, D. V. Ayollo, S. N. Rubtsova |
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Format: | Article |
Language: | Russian |
Published: |
ABV-press
2015-06-01
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Series: | Успехи молекулярной онкологии |
Subjects: | |
Online Access: | https://umo.abvpress.ru/jour/article/view/12 |
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