IgE-mediated food allergy

Abstract Food allergy is defined as an adverse immunologic response to a food protein. Food-related reactions are associated with a broad range of signs and symptoms that may involve any body system, including the skin, gastrointestinal and respiratory tracts, and cardiovascular system. Immunoglobul...

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Main Authors: Susan Waserman, Philippe Bégin, Wade Watson
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Allergy, Asthma & Clinical Immunology
Online Access:http://link.springer.com/article/10.1186/s13223-018-0284-3
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author Susan Waserman
Philippe Bégin
Wade Watson
author_facet Susan Waserman
Philippe Bégin
Wade Watson
author_sort Susan Waserman
collection DOAJ
description Abstract Food allergy is defined as an adverse immunologic response to a food protein. Food-related reactions are associated with a broad range of signs and symptoms that may involve any body system, including the skin, gastrointestinal and respiratory tracts, and cardiovascular system. Immunoglobulin E (IgE)-mediated food allergy is a leading cause of anaphylaxis and, therefore, referral to an allergist for timely and appropriate diagnosis and treatment is imperative. Diagnosis entails a careful history and diagnostic tests, such as skin prick tests, serum-specific IgE and, if indicated, an oral food challenge. Once the diagnosis of food allergy is confirmed, strict elimination of the offending food allergen from the diet is generally necessary; however, in the case of cow’s milk and egg allergy, many allergic children are able to eat these foods in their baked form. This article provides an overview of the epidemiology, pathophysiology, diagnosis, and management of IgE-mediated food allergy.
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spelling doaj.art-f35923f7f94d43ca87ffc692f6d0d2952022-12-22T00:20:58ZengBMCAllergy, Asthma & Clinical Immunology1710-14922018-09-0114S211110.1186/s13223-018-0284-3IgE-mediated food allergySusan Waserman0Philippe Bégin1Wade Watson2Division of Clinical Immunology and Allergy, Department of Medicine, McMaster UniversityDivision of Clinical Immunology and Allergy, Department of Medicine, Université de MontréalIWK Health Centre, Division of Allergy, Department of Pediatrics, Dalhousie UniversityAbstract Food allergy is defined as an adverse immunologic response to a food protein. Food-related reactions are associated with a broad range of signs and symptoms that may involve any body system, including the skin, gastrointestinal and respiratory tracts, and cardiovascular system. Immunoglobulin E (IgE)-mediated food allergy is a leading cause of anaphylaxis and, therefore, referral to an allergist for timely and appropriate diagnosis and treatment is imperative. Diagnosis entails a careful history and diagnostic tests, such as skin prick tests, serum-specific IgE and, if indicated, an oral food challenge. Once the diagnosis of food allergy is confirmed, strict elimination of the offending food allergen from the diet is generally necessary; however, in the case of cow’s milk and egg allergy, many allergic children are able to eat these foods in their baked form. This article provides an overview of the epidemiology, pathophysiology, diagnosis, and management of IgE-mediated food allergy.http://link.springer.com/article/10.1186/s13223-018-0284-3
spellingShingle Susan Waserman
Philippe Bégin
Wade Watson
IgE-mediated food allergy
Allergy, Asthma & Clinical Immunology
title IgE-mediated food allergy
title_full IgE-mediated food allergy
title_fullStr IgE-mediated food allergy
title_full_unstemmed IgE-mediated food allergy
title_short IgE-mediated food allergy
title_sort ige mediated food allergy
url http://link.springer.com/article/10.1186/s13223-018-0284-3
work_keys_str_mv AT susanwaserman igemediatedfoodallergy
AT philippebegin igemediatedfoodallergy
AT wadewatson igemediatedfoodallergy