Expression characteristics of interferon-stimulated genes and possible regulatory mechanisms in lupus patients using transcriptomics analyses

Expression characteristics of interferon-stimulated genes and possible regulatory mechanisms in lupus patients using transcriptomics analyses

Background: Type I interferon signature is one of the most important features of systemic lupus erythematosus (SLE), which indicates an active immune response to antigen invasion. Characteristics of type I interferon-stimulated genes (ISGs) in SLE patients have not been well described thus far. Meth...

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Bibliographic Details
Main Authors: Yiyao Deng, Ying Zheng, Delun Li, Quan Hong, Min Zhang, Qinggang Li, Bo Fu, Lingling Wu, Xu Wang, Wanjun Shen, Yingjie Zhang, Jiakai Chang, Kangkang Song, Xiaomin Liu, Shunlai Shang, Guangyan Cai, Xiangmei Chen
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:EBioMedicine
Subjects:
Single-cell RNA sequencing
Interferon
Granulocytes
Systemic lupus erythematosus
Lupus nephritis
Online Access:http://www.sciencedirect.com/science/article/pii/S235239642100270X

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http://www.sciencedirect.com/science/article/pii/S235239642100270X

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