Lung Spatial Profiling Reveals a T Cell Signature in COPD Patients with Fatal SARS-CoV-2 Infection

Lung Spatial Profiling Reveals a T Cell Signature in COPD Patients with Fatal SARS-CoV-2 Infection

People with pre-existing lung diseases such as chronic obstructive pulmonary disease (COPD) are more likely to get very sick from SARS-CoV-2 disease 2019 (COVID-19). Still, an interrogation of the immune response to COVID-19 infection, spatially throughout the lung structure, is lacking in patients...

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Bibliographic Details
Main Authors: Chen Xi Yang, Michael Tomchaney, Manuel F. Landecho, Borja R. Zamacona, Marta Marin Oto, Javier Zulueta, Joshua Malo, Steve Knoper, Marco Contoli, Alberto Papi, Dragoş M. Vasilescu, Maor Sauler, Christof Straub, Cheryl Tan, Fernando D. Martinez, Deepta Bhattacharya, Ivan O. Rosas, Farrah Kheradmand, Tillie-Louise Hackett, Francesca Polverino
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
COVID-19
chronic obstructive pulmonary disease (COPD)
T cells
Online Access:https://www.mdpi.com/2073-4409/11/12/1864

Internet

https://www.mdpi.com/2073-4409/11/12/1864

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