Validation of AmpliSeq NGS Panel for <i>BRCA1</i> and <i>BRCA2</i> Variant Detection in Canine Formalin-Fixed Paraffin-Embedded Mammary Tumors

Validation of AmpliSeq NGS Panel for <i>BRCA1</i> and <i>BRCA2</i> Variant Detection in Canine Formalin-Fixed Paraffin-Embedded Mammary Tumors

Mammary carcinomas are the most common neoplasms observed in women and in female dogs. Canine mammary tumors show epidemiological, clinical, genetic, and prognostic characteristics comparable to human breast cancers. The recent introduction of next generation sequencing (NGS) technologies has greatl...

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Bibliographic Details
Main Authors: Daniela Di Giacomo, Marco Di Domenico, Sabrina Vanessa Patrizia Defourny, Daniela Malatesta, Giovanni Di Teodoro, Michele Martino, Antonello Viola, Nicola D’Alterio, Cesare Cammà, Paola Modesto, Antonio Petrini
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Life
Subjects:
CMTs
FFPE
validation
repeatability
dog tumors
Online Access:https://www.mdpi.com/2075-1729/12/6/851

Internet

https://www.mdpi.com/2075-1729/12/6/851

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