Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1

Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1

Abstract Chronic kidney disease (CKD) and the genetic disorder myotonic dystrophy type 1 (DM1) each are associated with progressive muscle wasting, whole-body insulin resistance, and impaired systemic metabolism. However, CKD is undocumented in DM1 and the molecular pathogenesis driving DM1 is unkno...

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Bibliografiska uppgifter
Huvudupphovsmän: Preeti Kumari, Lauren M. Sullivan, Zhaozhi Li, E. Parker Conquest, Elizabeth Cornforth, Rojashree Jayakumar, Ningyan Hu, J. Alexander Sizemore, Brigham B. McKee, Robert R. Kitchen, Paloma González-Pérez, Constance Linville, Karla Castro, Hilda Gutierrez, Soleil Samaan, Elise L. Townsend, Basil T. Darras, Seward B. Rutkove, Susan T. Iannaccone, Paula R. Clemens, Araya Puwanant, Sudeshna Das, Thurman M. Wheeler
Materialtyp: Artikel
Språk:English
Publicerad: Nature Portfolio 2025-03-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-025-56479-5

Internet

https://doi.org/10.1038/s41467-025-56479-5

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