scCODA is a Bayesian model for compositional single-cell data analysis

Imbalance and loss of cell types is a hallmark in many diseases. Still, quantifying compositional changes in scRNAseq data remains challenging. Here the authors present scCODA, a Bayesian model to assess cell type compositions in scRNA-seq data.

Bibliographic Details
Main Authors: M. Büttner, J. Ostner, C. L. Müller, F. J. Theis, B. Schubert
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27150-6