Expansion of Activated Lymphocytes Obtained from Renal Cell Carcinoma in an Automated Hollow Fiber Bioreactor

Immunotherapy using IL-2 alone or combined with activated lymphocytes has been promising for metastatic renal cell carcinoma. Cytotoxic lymphocytes can be isolated from tumors, expanded in vitro with IL-2, and adoptively transferred back into the tumor-bearing host. These cells can also be transduce...

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Bibliographic Details
Main Authors: Gilda G. Hillman Ph.D., Martin L. Wolf, Emily Montecillo, Elia Younes, Esa Ali, J. Edson Pontes, Gabriel P. Haas
Format: Article
Language:English
Published: SAGE Publishing 1994-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979400300402