Characterization of the First Animal Toxin Acting as an Antagonist on AT1 Receptor

Characterization of the First Animal Toxin Acting as an Antagonist on AT1 Receptor

The renin-angiotensin system (RAS) is one of the main regulatory systems of cardiovascular homeostasis. It is mainly composed of angiotensin-converting enzyme (ACE) and angiotensin II receptors AT1 and AT2. ACE and AT1 are targets of choice for the treatment of hypertension, whereas the AT2 receptor...

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Bibliographic Details
Main Authors: Anne-Cécile Van Baelen, Xavier Iturrioz, Marion Chaigneau, Pascal Kessler, Catherine Llorens-Cortes, Denis Servent, Nicolas Gilles, Philippe Robin
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
conotoxin
angiotensin
AT1
GPCR
<i>Conus miliaris</i>
Online Access:https://www.mdpi.com/1422-0067/24/3/2330

Internet

https://www.mdpi.com/1422-0067/24/3/2330

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