Three-dimensional morphodynamic simulations of macropinocytic cups

Summary: Macropinocytosis refers to the non-specific uptake of extracellular fluid, which plays ubiquitous roles in cell growth, immune surveillance, and virus entry. Despite its widespread occurrence, it remains unclear how its initial cup-shaped plasma membrane extensions form without any external...

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Bibliographic Details
Main Authors: Nen Saito, Satoshi Sawai
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221010555