Therapeutic Implications of Targeting Heat Shock Protein 70 by Immunization or Antibodies in Experimental Skin Inflammation

Therapeutic Implications of Targeting Heat Shock Protein 70 by Immunization or Antibodies in Experimental Skin Inflammation

Heat shock proteins (Hsp) are constitutive and stress-induced molecules which have been reported to impact innate and adaptive immune responses. Here, we evaluated the role of Hsp70 as a treatment target in the imiquimod-induced, psoriasis-like skin inflammation mouse model and related in vitro assa...

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Bibliographic Details
Main Authors: Stefan Tukaj, Jagoda Mantej, Michał Sobala, Katarzyna Potrykus, Zbigniew Tukaj, Detlef Zillikens, Ralf J. Ludwig, Katja Bieber, Michael Kasperkiewicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
psoriasis
regulatory T cells
Treg
Th17
heat shock proteins
Hsp70
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.614320/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.614320/full

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