Identification and distribution of gene clusters required for synthesis of sphingolipid metabolism inhibitors in diverse species of the filamentous fungus Fusarium

Identification and distribution of gene clusters required for synthesis of sphingolipid metabolism inhibitors in diverse species of the filamentous fungus Fusarium

Abstract Background Sphingolipids are structural components and signaling molecules in eukaryotic membranes, and many organisms produce compounds that inhibit sphingolipid metabolism. Some of the inhibitors are structurally similar to the sphingolipid biosynthetic intermediate sphinganine and are re...

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Bibliographic Details
Main Authors: Hye-Seon Kim, Jessica M. Lohmar, Mark Busman, Daren W. Brown, Todd A. Naumann, Hege H. Divon, Silvio Uhlig, Robert H. Proctor
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Genomics
Subjects:
Fusarium
Genome sequence
Secondary metabolite
Sphinganine analog
Biosynthetic gene cluster
Horizontal gene transfer
Online Access:http://link.springer.com/article/10.1186/s12864-020-06896-1

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http://link.springer.com/article/10.1186/s12864-020-06896-1

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