The role of agonistic/antagonistic activity in the development of psychotropic effects of antipsychotics

The development of psychotic symptoms is traditionally linked to the increase of the functional activity of endogenous dopaminergic system. Antipsychotic effect of existing medications is associated with direct blockade of postsynaptic dopamine receptors. However, direct antagonistic activity is «al...

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Bibliographic Details
Main Authors: V. I. Kozlovskiy, D. N. Kosterin, M. Yu. Popov
Format: Article
Language:Russian
Published: Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation 2019-05-01
Series:Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
Subjects:
Online Access:https://www.bekhterevreview.com/jour/article/view/227