Influence of ceftriaxone on human bone cell viability and in vitro mineralization potential is concentration- and time-dependent

Aims: In orthopaedic and trauma surgery, implant-associated infections are increasingly treated with local application of antibiotics, which allows a high local drug concentration to be reached without eliciting systematic adverse effects. While ceftriaxone is a widely used antibiotic agent that ha...

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Bibliographic Details
Main Authors: Matthias Guido Wiesli, Jean-Pierre Kaiser, Emanuel Gautier, Peter Wick, Katharina Maniura-Weber, Markus Rottmar, Peter Wahl
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2021-03-01
Series:Bone & Joint Research
Subjects:
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.103.BJR-2020-0412