The Role of Apoptotic Signaling in Axon Guidance

The Role of Apoptotic Signaling in Axon Guidance

Navigating growth cones are exposed to multiple signals simultaneously and have to integrate competing cues into a coherent navigational response. Integration of guidance cues is traditionally thought to occur at the level of cytoskeletal dynamics. Drosophila studies indicate that cells exhibit a lo...

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Bibliographic Details
Main Authors: Riley Kellermeyer, Leah M. Heydman, Grant S. Mastick, Thomas Kidd
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Journal of Developmental Biology
Subjects:
axon guidance
growth cone
cytoskeleton
caspases
apoptosis
signal integration
basal level of caspase activity
death associated inhibitor of apoptosis
axon branching
Netrin
DCC
Frazzled
Slit
Robo
Drosophila
Online Access:http://www.mdpi.com/2221-3759/6/4/24

Internet

http://www.mdpi.com/2221-3759/6/4/24

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