Deciphering the Glycosylation Steps in the Biosynthesis of P-1894B and Grincamycin Isolated from Marine-Derived <i>Streptomyces lusitanus</i> SCSIO LR32

Recently, we re-isolated the glycosylated angucycline antibiotics P-1894B (<b>1</b>) and grincamycin (<b>1′</b>) from the marine-derived <i>Streptomyces lusitanus</i> SCSIO LR32 as potent antitumor agents and identified their biosynthesis gene cluster <i>gcn...

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Bibliographic Details
Main Authors: Hongbo Huang, Yun Zhang, Yongxiang Song, Chunyao Ling, Siyan Peng, Bo Ding, Yiwen Tao, Jianhua Ju
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/22/1/32