STmut: a framework for visualizing somatic alterations in spatial transcriptomics data of cancer

Abstract Spatial transcriptomic technologies, such as the Visium platform, measure gene expression in different regions of tissues. Here, we describe new software, STmut, to visualize somatic point mutations, allelic imbalance, and copy number alterations in Visium data. STmut is tested on fresh-fro...

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Bibliographic Details
Main Authors: Limin Chen, Darwin Chang, Bishal Tandukar, Delahny Deivendran, Joanna Pozniak, Noel Cruz-Pacheco, Raymond J. Cho, Jeffrey Cheng, Iwei Yeh, Chris Marine, Boris C. Bastian, Andrew L. Ji, A. Hunter Shain
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-023-03121-6