Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens

ABSTRACT Human norovirus interacts with the polymorphic human histo-blood group antigens (HBGAs), and this interaction is thought to be important for infection. The genogroup II genotype 4 (GII.4) noroviruses are the dominant cluster, evolve every other year, and are thought to modify their binding...

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Bibliographic Details
Main Authors: Bishal K. Singh, Mila M. Leuthold, Grant S. Hansman
Format: Article
Language:English
Published: American Society for Microbiology 2016-04-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00049-16