Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer’s Disease Patients

Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer’s Disease Patients

Olfaction is orchestrated by olfactory mucosal cells located in the upper nasal cavity. Olfactory dysfunction manifests early in several neurodegenerative disorders including Alzheimer’s disease, however, disease-related alterations to the olfactory mucosal cells remain poorly described. The aim of...

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Bibliographic Details
Main Authors: Riikka Lampinen, Mohammad Feroze Fazaludeen, Simone Avesani, Tiit Örd, Elina Penttilä, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Liudmila Saveleva, Emma Kaartinen, Francisco Fernández Acosta, Marcela Cruz-Haces, Heikki Löppönen, Alan Mackay-Sim, Minna U. Kaikkonen, Anne M. Koivisto, Tarja Malm, Anthony R. White, Rosalba Giugno, Sweelin Chew, Katja M. Kanninen
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
Alzheimer’s disease
olfactory mucosa
amyloid beta
single-cell RNA-sequencing
mitochondria
Online Access:https://www.mdpi.com/2073-4409/11/4/676

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https://www.mdpi.com/2073-4409/11/4/676

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