Semi-Synthesis of Harringtonolide Derivatives and Their Antiproliferative Activity
Harringtonolide (HO), a natural product isolated from <i>Cephalotaxus harringtonia</i>, exhibits potent antiproliferative activity. However, little information has been reported on the systematic structure−activity relationship (SAR) of HO derivatives. Modifications on tropone, lactone,...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/5/1380 |