Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): A review and novel case with dual germline SMARCA4 and BRCA2 mutations

Small cell carcinoma of the ovary hypercalcemic type (SCCOHT): A review and novel case with dual germline SMARCA4 and BRCA2 mutations

Small cell carcinoma of the ovary hypercalcemic type (SCCOHT) is a rare and aggressive disease. While classically linked to mutations in SMARCA4, we describe a case in a patient with both SMARCA4 and BRCA2 germline mutations. We describe her disease presentation, histopathology and treatment with ad...

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Bibliographic Details
Main Authors: Brooke E. Sanders, Rebecca Wolsky, Elizabeth S. Doughty, Kristen L. Wells, Debashis Ghosh, Lisa Ku, Joseph G. Pressey, Benjamin G. Bitler, Lindsay W. Brubaker
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Gynecologic Oncology Reports
Subjects:
Small cell carcinoma of the ovary
PARP inhibitor
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578922001576

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http://www.sciencedirect.com/science/article/pii/S2352578922001576

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