Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Response to Omega-3 Fatty Acid Supplementation.

There is a high degree of inter-individual variability among people in response to intervention with omega-3 fatty acids (FA), which may partly explain conflicting results on the effectiveness of omega-3 FA for the treatment and prevention of chronic inflammatory diseases. In this study we sought to...

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Main Authors: Claire C Berthelot, Shizuo George Kamita, Romina Sacchi, Jun Yang, Malin L Nording, Katrin Georgi, Christine Hegedus Karbowski, J Bruce German, Robert H Weiss, Ronald J Hogg, Bruce D Hammock, Angela M Zivkovic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4681469?pdf=render