An immune-competent human gut microphysiological system enables inflammation-modulation by Faecalibacterium prausnitzii
Abstract Crosstalk of microbes with human gut epithelia and immune cells is crucial for gut health. However, there is no existing system for a long-term co-culture of human innate immune cells with epithelium and oxygen-intolerant commensal microbes, hindering the understanding of microbe-immune int...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
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Series: | npj Biofilms and Microbiomes |
Online Access: | https://doi.org/10.1038/s41522-024-00501-z |