Maternal 3,3-Dimethyl-1-Butanol Therapy Protects Adult Male Rat Offspring against Hypertension Programmed by Perinatal TCDD Exposure

Maternal 3,3-Dimethyl-1-Butanol Therapy Protects Adult Male Rat Offspring against Hypertension Programmed by Perinatal TCDD Exposure

Maternal exposure to environmental pollutants affects fetal development, which can result in hypertension in adulthood. Gut microbiota-derived metabolite trimethylamine (TMA), trimethylamine-N-oxide (TMAO), and short chain fatty acids (SCFAs) have been associated with hypertension. We tested a hypot...

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Bibliographic Details
Main Authors: Chien-Ning Hsu, Chih-Yao Hou, Chien-Te Lee, Guo-Ping Chang-Chien, Sufan Lin, You-Lin Tain
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Nutrients
Subjects:
gut microbiota
aryl hydrocarbon receptor
3,3-dimethyl-1-butanol
developmental origins of health and disease (DOHaD)
hypertension
short chain fatty acid
Online Access:https://www.mdpi.com/2072-6643/13/9/3041

Internet

https://www.mdpi.com/2072-6643/13/9/3041

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