Chronic ethanol increases systemic TLR3 agonist-induced neuroinflammation and neurodegeneration

<p>Abstract</p> <p>Background</p> <p>Increasing evidence links systemic inflammation to neuroinflammation and neurodegeneration. We previously found that systemic endotoxin, a TLR4 agonist or TNFα, increased blood TNFα that entered the brain activating microglia and per...

Full description

Bibliographic Details
Main Authors: Qin Liya, Crews Fulton T
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/9/1/130