Automated synthesis of [68Ga]Ga-FAPI-46 without pre-purification of the generator eluate on three common synthesis modules and two generator types

Automated synthesis of [68Ga]Ga-FAPI-46 without pre-purification of the generator eluate on three common synthesis modules and two generator types

Abstract Background The recent development of quinoline-based radiotracers, which act as fibroblast activation protein inhibitors (FAPIs), has shown promising preclinical and clinical advantages. [68Ga]Ga-FAPI-46 is a new radiotracer for in vivo detection of the fibroblast activation protein by posi...

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Bibliographic Details
Main Authors: Ammar Alfteimi, Ulf Lützen, Alexander Helm, Michael Jüptner, Marlies Marx, Yi Zhao, Maaz Zuhayra
Format: Article
Language:English
Published: SpringerOpen 2022-07-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Automated radiosynthesis
FAPI-46
Fibroblast
Gallium-68
Online Access:https://doi.org/10.1186/s41181-022-00172-1

Internet

https://doi.org/10.1186/s41181-022-00172-1

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