The DUX4–HIF1α Axis in Murine and Human Muscle Cells: A Link More Complex Than Expected

The DUX4–HIF1α Axis in Murine and Human Muscle Cells: A Link More Complex Than Expected

FacioScapuloHumeral muscular Dystrophy (FSHD) is one of the most prevalent inherited muscle disorders and is linked to the inappropriate expression of the DUX4 transcription factor in skeletal muscles. The deregulated molecular network causing FSHD muscle dysfunction and pathology is not well unders...

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Bibliographic Details
Main Authors: Thuy-Hang Nguyen, Maelle Limpens, Sihame Bouhmidi, Lise Paprzycki, Alexandre Legrand, Anne-Emilie Declèves, Philipp Heher, Alexandra Belayew, Christopher R. S. Banerji, Peter S. Zammit, Alexandra Tassin
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
FSHD
DUX4
HIF1α
myogenesis
skeletal muscle
Online Access:https://www.mdpi.com/1422-0067/25/6/3327

Internet

https://www.mdpi.com/1422-0067/25/6/3327

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