Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation

The adult mammalian heart exhibits limited regenerative capacity after myocardial injury, a shortcoming that is responsible for the current lack of definitive treatments for heart failure. A search for approaches that might enhance adult heart regeneration has led to interest in the Hippo/Yap signal...

Full description

Bibliographic Details
Main Authors: Zhiqiang Lin, William T. Pu
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114000464